Synthesis of Schiff base and its T. M. and lanthanide complexes
SYNTHESIS AND CHARACTERIZATION OF BENZOCAINE SCHIFF BASE AND ITS COBALT COMPLEX
-
Research Summary
Ethyl4-(2-hydroxy-benzylideneamino) benzoate Schiff base (C16H15NO3), were synthesized and the structure was studied against the bases of X-ray, UV, visible, elemental analysis, 1HNMR, IR and Mass spectroscopy. The crystal structure of the nickel complex has been determined by single crystal X-ray conformed the molecule, which indicate the compound is crystalline in the monoclinic C2 / c with a = 16.0916 (5) Å, b = 6.0315 (2) Å, c =29.0072 (10) Å, α = 90.00°, β= 101.856 (2)°, γ = 90.00°, V= 2755.3 (2) Å3 and Z = 8. Because of intra-molecular hydrogen bond involving the O atom of hydroxy group and N atom of azomethine group; the two benzene rings and azomethine group are practically coplanar. The Cobalt complex was prepared; the structure was characterized in the bases of IR spectra, elemental analysis, UV - visible, and conductance measurements. Also, the biological activity of both Schiff base and its Cobalt complex show that they are biologically active.
- Search Link
- key words
Spectroscopic, Benzocaine, Schiff base, X-ray single crystal, Biological activities and Cobalt complex
The crystal structure of ethyl 4-((2-hydroxybenzyl)amino)benzoate, a Schiff base, C16H17NO3
-
Research Summary
C16H17NO3, triclinic, P1̅ (no. 2), a = 7.5445(7) Å, b = 8.3326(9) Å, c = 12.4291(10) Å, α = 94.468(8)°, β = 91.063(7)°, γ = 116.644(10)°, V = 695.01(13) Å3, Z = 2, Rgt(F) = 0.0461, wRref(F2) = 0.1240, T = 291 K. The asymmetric unit of the title crystal structure is shown in the figure. Tables 1 and 2 contain details of the measurement method and a list of the atoms including atomic coordinates and displacement parameters.
- Search Link
- key words
Crystal structure , Schiff base
Synthesis of 2-{(Z)-[(4-methylphenyl)imino]methyl}phenol Schiff base
-
Research Summary
2-{(Z)-[(4-methylphenyl)imino]methyl}phenol Schiff base (C14H13NO),were synthesized and the structure was
elucidated in the bases of 1HNMR and X-ray. The X-ray establish the conformation of the molecule, which indicate
the compound is crystalline in the monoclinic P 21/c with a = 19.3092(19) Å, b = 4.7611(4) Å, c = 12.2222(11) Å a
= 90°, b = 102.087(10)°, g = 90°and Z = 4. Two benzene rings and azomethine group are practically coplanar, as
a result of intramolecular hydrogen bond involving the O atom of hydroxyl group and N atom of azomethine group.
- Search Link
- key words
Salicylaldehyde, p-Toluidine, Schiff base and x-ray
Synthesis and Spectroscopic Characterization of
Tris(hydroxymethyl)aminomethane Proton Transfer Complexes
with Acidic π-Acceptors
-
Research Summary
Two charge transfer complexes based on an organic basic donor, tris(hydroxymethyl)-
aminomethane (Tris), and two π-acceptors having acidic protons, picric acid (PA) and
chloroanilic acid (CA), were synthesized for the first time. Some physicochemical analyses
including UV-Vis, FT-IR and 1H-NMR were employed to investigate and confirm the proposed
chemical structures of the prepared complexes. It was found that the donor–acceptor molar ratio
is 1:1 for Tris:PA and 1:2 for Tris:CA charge transfer complexes. The formed charge transfer
complexes have –NH3
+
and –OH2
+ ions as a result of proton transfer from acidic to basic
centers. The formation constant (KCT) and molar absorptivity coefficient (CT) were calculated
from the experimental spectroscopic data. Thermodynamic studies for both charge transfer
complexes showed the favorability of the complex formation.
- Search Link
- key words
Charge transfer complexes, π-acceptors; Tris(hydroxymethyl)aminomethane; Picric acid and Chloroanilic acid.
Reduced Schiff base zinc complexes as proposed models of the active
site of the dinuclear zinc enzyme A. Aminopeptidase
-
Research Summary
Complexes of zinc with ligands prepared through the reduction of Schiff bases derived from salicylaldehyde and the
primary aliphatic amines 1,4-diaminobutane (H2Salbn), 1,6-diaminohexane (H2Salhx), and tris(hydroxymethyl)
aminomethane (H2Saltris) have been prepared and proposed as models of the active site of the zinc enzyme
Aeromonas Proteolytica aminopeptidase. The complexes were characterized by 1H-NMR, FT-IR spectroscopy, and
mass spectrometry. In complexes of both H2Salbn and H2Salhx, the 5-ccordinate zinc atoms are present in a N,O
environment with bridging carboxylate ligands thus providing close analogues to the enzyme's active site. On the
other hand, the complex of H2Saltris contains one zinc atom with an all-oxygen environment and one zinc atom
bound to one N and five O atoms.
- Search Link
- key words
dinuclear zinc complexes, Reduced Schiff bases, models of enzymes, amino alcohol complexes,
Aeromonas aminopeptidase.
Synthesis and Characterization of β-Diketimine Schiff Base Complexes with Ni(II) and Zn(II) Ions: Experimental and Theoretical Study
-
Research Summary
Schiff base diethyl 4,4-(pentane-2,4-diylidenebis(azanylylidene))benzoate (1) as a new ligand (L) was prepared by the reaction of acetylacetone with benzocaine in the ratio of 1 :1. Two transition-metal complexes, [Ni(II)(LCl(HOEt))] (2) and [Zn(II)(LCl(HOEt))] (3), have been synthesized from metal salts with didentate Schiff base ligand (L) and characterized by elemental analyses, FT-IR, 1H NMR, 13C NMR UV-Vis spectroscopy, and magnetic susceptibility. +e biological activity of the complexes was studied. In addition, the M06-2x density function theory method and the 6-31G(d) basic set were applied to determine the optimized structures of 1–3 and to determine their IR and 1 H NMR, 13C NMR spectra theoretically. +e data are in good agreement with the experimental results. +e geometries of complexes 2 and 3 were determined to be square-planar for 2 and tetrahedral for 3
- Search Link
- key words
Schiff base. acetylacetone, Nickle complex
SYNTHESIS, CHARACTERIZATION, CRYSTAL STRUCTURE AND
FLUORESCENCEOFANEWSAMARIUMSCHIFF-BASECOMPLEX
-
Research Summary
A new samarium Schiff base complex with the formula [SmIII(NO3)3(H2O)L2]⋅EtOH, where L = {(E)-2-
(((4-(ethoxycarbonyl)phenyl)iminio)-methyl)phenolate}, is synthesized. Its molecular structure is
determined by means of single crystal X-ray diffraction (XRD). The complex crystallizes in the
orthorhombic space group Pbca with the following unit cell dimensions: a = 14.1304(19) Å,
b = 18.0218(13) Å, and c = 31.246(2) Å. Photoluminescence characteristics of the complex are investigated
experimentally in the solid state and obtained theoretically using the Sparkle/PM7 modeling. Moreover,
several methods such as powder XRD, FT-IR and UV-Visible spectroscopy are utilized to confirm the
structure of the complex
- Search Link
- key words
samarium, Schiff base, fluorescence, crystal structure, Sparkle/PM7
Proton transfer complexes based on some π-acceptors having acidic protons
with tyramine donor: Synthesis and spectroscopic characterizations
-
Research Summary
Charge transfer complexes based on tyramine (Ty) (4-(2-aminoethyl) phenol) organic basic donor and π -acceptors
having acidic protons such as picric acid (PA), and chloroanilic acid (CA) with the compositions, [(Ty)(CA)2] and
[(Ty)(PA)2] have been synthesized and the chemical structures were confirmed by thermal analysis and
physicochemical studies such as UV visible, FT-IR and 1H-NMR spectral studies. Spectroscopy measurements show
that the donor–acceptor molar ratio was found to be 1: 2 for both (Ty): (PA) and (Ty): (CA) charge transfer
complexes, in addition to that the ArNH+
3 ammonium ion and OH2+ were formed under the acid–base theory
through proton transfer from an acidic to basic centers in charge transfer complexes, as well as the spectroscopic
data were discussed in terms of formation constant (KCT) and molar extinction coefficient (εCT). Thermal behavior of
both charge transfer complexes showed that the complexes were more stable than their parents.
- Search Link
- key words
Charge transfer complexes, Tyramine, picric acid and chloroanilic acid.
_________________________________________________________________