أستاذ دكتور
د. اسامه يوسف ابراهيم الذنيبات

  • السيرة الذاتية
  • التخصص: العلوم الطبية الحيوية
  • الكلية: كلية الأميرة عائشة بنت الحسين للتمريض والعلوم الصحية
  • القسم : قسم التحاليل الطبية
  • البريد الالكتروني: Osama.y.althunibat@ahu.edu.jo
  • رقم الهاتف: 00962770692169

الدكتور أسامه يوسف الذنيبات من مواليد قرية الجديدة في محافظة الكرك عام 1978, وحاصل على درجة الدكتوراة في العلوم الطبية الحيوية من الجامعة العالمية الإسلامية في ماليزيا عام 2012. ودرجة الماجستير في العلوم الحياتية من جامعة مؤتة عام 2006 والبكالوريوس في الطب والجراحة البيطرية من جامعة العلوم والتكنولوجيا الاردنية عام 2001. عمل في كمدرس مساعد ومحاضر غير متفرغ أثناء دراسته للدكتوراة  في الجامعة العالمية الاسلامية في ماليزيا. و التحق بالعمل كأستاذ مساعد في كلية الصيدلة بجامعة الزيتونة الأردنية الخاصة بعد حصوله على درجة الدكتوراة عام 2012 واستمر فيها حتى نهاية العام الدراسي 2014-2015. حيث انتقل بعدها للعمل كأستاذ مساعد في قسم التحاليل الطبية بجامعة الحسين بن طلال. كما وتم تكليفه برئاسة قسم التحاليل الطبية  في الجامعة خلال العام الدراسي 2016-2017.
عمل الدكتور  أثناء مسيرته الأكاديمية على تدريس العديد من المواد ضمن مجال تخصصه في العلوم الطبية الحيوية بما فيها مواد الكيمياء الحيوية الطبية والكيمياء السريرية وعلم الأمراض والفسيولوجيا المرضية. كما وقد ساهم في العديد من الأبحاث في مجالات  العلوم الطبية الأساسية والتي نشرت نتائجها بأكثر من عشرين ورقة بحثية في مجلات علمية دولية محكمة إضافة الى المشاركة بعدد من المؤتمرات الدولية لتقديم  ومناقشة نتائج بعض أبحاثه.
حصل الدكتور اسامة الذنيبات على جائزة أفضل بحث مقدم (الجائزة الذهبية) في في معرض الأبحاث والإبتكار في الجامعة العالمية الإسلامية في ماليزيا (IRIIE 2011) عام 2011. كما وحصل على منحة دراسية من الجامعة العالمية الإسلامية في ماليزيا في منحة مقدمة لللأبحاث في المجالات الرائدة (Nich Area Scholarship, IIUM, 2010/2011) لإتمام دراستة في الدكتوراة.
ويشارك الدكتور اسامه الذنيبات في البرامج والنشاطات التوعوية والصحية التي تنظمها جامعة الحسين والمؤسسات الوطنية الأخرى كإعطاء المحاضرات التوعوية والتثقيفية ولإشراف على أجراء الفحوصات الطبيىة في الأيام الطبية المجانية المقدمة الى المجتمع المحلي. 

Pharmaceutical effects of natural products

 Effects of leptin hormone on obesity and lipid profile 

The prevalence of genetic and nutritional disorders in the south Jordan population

5. Alkhamaiseh S. I., Taher M., Farediah A., Qaralleh H., Althunibat O.Y., Deny Susanti D. and Solachuddin Jauhari Arief Ichwan S. J. (2012). The phytochemical content and antimicrobial activities of Malaysian Calophyllum canum (stem bark). Pakistan Journal of Pharmaceutical Sciences, 25 (3): 555-563.
Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes
  • ملخص البحث
  • Medicinal plants are being used extensively in Jordanian traditional medicinal system for the treatment of diabetes symptoms. Twenty one plant samples were collected from different Jordanian locations and used for antioxidant evaluation. The level of antioxidant activity was determined by DPPH and ABTS assays in relation to the total phenolic contents of the medically used parts. The most frequently used plant parts as medicines were fruit, shoot and leaves. The total phenolic contents of methanol and aqueous extracts, from plants parts, ranged from 6.6 to 103.0 and 3.0 to 98.6 GAE mg g(-1) of plant part dry weight, respectively. DPPH-TEAC of the methanol extracts of plants parts were varied from 4.1 to 365.0 mg g(-1) of plant dry weight versus 0.6 to 267.0 mg g(-1) in aqueous extracts. Moreover, the mean values of ABTS*- (IC50) varied from 6.9 to 400.0 microg dry weight mL(-1) ABTS in methanol extracts versus 9.8 to 580.5 microg mL(-1) in aqueous extracts. According to their antioxidant capacity, the plants were divided into three categories: high (DPPH-TEAC > or = 80 mg g(-1) ), (i.e., Punica granatum peel, Quercus calliprinos leave, Quercus calliprinos fruit, Cinchona ledgeriana and Juniperus communis leave), moderate (DPPH-TEAC range 20-80 mg g(-1)) (i.e., Salvia fruticosa shoot, Crataegus azarolus stem, Crataegus azarolus leave, Varthemia iphionoides shoot, Artemisia herba-alba shoot, Thymus capitatus shoot, Morus nigra leaves and Arum palaestinum leaves) and low antioxidant plants (DPPH-TEAC < 20 mg g(-1)), (i.e., Matricaria aurea shoot, Artemisia judaica shoot, Teucrium polium shoot, Pinus halepenss pollen grains, Sarcopoterium spinosum root, Crataegus azarolus fruit, Inula viscose shoot and Achillea fragrantissima shoot). The antioxidant activity of these plant's extracts and their potential rule in radical scavenging agreed with their potential use by Jordanian population as a traditional anti-diabetic agents.
  • رابط البحث
  • الكلمات المفتاحية
    antioxidant, DPPH, ABTS, TEAC, Polyphenols, GAE, Jordan
In vitro antioxidant and antiproliferative activities of three Malaysian sea cucumber species
  • ملخص البحث
  • The antioxidant and antiproliferative activities of aqueous and organic extracts from three sea cucumber species, Holothuria scabra, Holothuria leucospilota and Stichopus chloronotus were studied. The result showed that aqueous extract of H. leucospilota contains the highest level of total phenols (9.7 mg GAE/g), while the lowest level was obtained from organic extract of H. scabra (1.53 mg GAE/g). An aqueous extract of S. chloronotus was the most efficient extract in scavenging of DPPH free radical, giving IC50= 2.13 mg/ml. The aqueous extracts (50mg/ml) of H. scabra, H. leucospilota and S. chloronotus exhibited high antioxidant activities (77.46%, 64.03% and 80.58%, respectively) against linoleic acid free radical. Only an aqueous extract of S. chloronotus inhibited growth of C33A (human cervical cancer) and A549 (human non-small lung carcinoma) cancer
  • رابط البحث
  • الكلمات المفتاحية
    Sea cucumber, Antioxidant, Antiproliferation.
Antibacterial activity in vitro of Thymus capitatus from Jordan.
  • ملخص البحث
  • This study was carried out to evaluate the antibacterial activity of aqueous and organic extracts of Thymus capitatus L.(Lamiaceae) leaves and stems. Dried ground powder leaves and stems were extracted with water (aqueous extracts), ethanol, dichloromethane and hexane (Soxhlet extracts). The antibacterial activity of these extracts was evaluated against bacteria using disc diffusion method. The result obtained showed that the leaves had stronger antibacterial activity than the stems extracts. The ethanolic extract had the highest yield products and the high antibacterial activity than all other solvents. The results suggest that essential oil as non-polar organic compounds could be the main active compounds in this plant. Therefore the antibacterial activity of leaves ethanol extracts (LEE) was compared with essential oils leaves extracts (LEO) of T. capitatus. The LEO showed greater …
  • رابط البحث
  • الكلمات المفتاحية
    Thymus capitatus, antibacterial, soxhlet extraction, essential oil.
1. Almustafah, A. and Althunibat, O.Y., (2009). Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes. Pakistan Journal of Boilogical Sciences,11 (3): 351-358.
2. Althunibat O.Y., Ridzwan B.H., Taher M., Daud J.M., Ikeda M.A., and Zali B.I. (2009). In Vitro Antioxidant and Antiproliferative Activities of Three Malaysian Sea Cucumber Species. European Journal of Scientific Research, 37 (3): 376-387.
3. Qaralleh H.N., Abboud M.M., Khleifat K., Tarawneh K.A., and Althunibat O.Y., (2009). Antibacterial activity in vitro of Thymus capitatus from Jordan. Pakistan Journal of Pharmaceutical Sciences, 2 (3): 247-251
Althunibat, O. Y., Almustafah, A., Tarawneh K., Khlefat K., Ridzwan B. H., and Qaralleh H. (2010). Protective role of Punica granatum L. peel extract against oxidative damage in experimental diabetic rats. Process Biochemistry, 45: 581-585.
5. Alkhamaiseh S. I., Taher M., Farediah A., Qaralleh H., Althunibat O.Y., Deny Susanti D. and Solachuddin Jauhari Arief Ichwan S. J. (2012). The phytochemical content and antimicrobial activities of Malaysian Calophyllum canum (stem bark). Pakistan Journal of Pharmaceutical Sciences, 25 (3): 555-563.
Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes
  • ملخص البحث
  • Medicinal plants are being used extensively in Jordanian traditional medicinal system for the treatment of diabetes symptoms. Twenty one plant samples were collected from different Jordanian locations and used for antioxidant evaluation. The level of antioxidant activity was determined by DPPH and ABTS assays in relation to the total phenolic contents of the medically used parts. The most frequently used plant parts as medicines were fruit, shoot and leaves. The total phenolic contents of methanol and aqueous extracts, from plants parts, ranged from 6.6 to 103.0 and 3.0 to 98.6 GAE mg g(-1) of plant part dry weight, respectively. DPPH-TEAC of the methanol extracts of plants parts were varied from 4.1 to 365.0 mg g(-1) of plant dry weight versus 0.6 to 267.0 mg g(-1) in aqueous extracts. Moreover, the mean values of ABTS*- (IC50) varied from 6.9 to 400.0 microg dry weight mL(-1) ABTS in methanol extracts versus 9.8 to 580.5 microg mL(-1) in aqueous extracts. According to their antioxidant capacity, the plants were divided into three categories: high (DPPH-TEAC > or = 80 mg g(-1) ), (i.e., Punica granatum peel, Quercus calliprinos leave, Quercus calliprinos fruit, Cinchona ledgeriana and Juniperus communis leave), moderate (DPPH-TEAC range 20-80 mg g(-1)) (i.e., Salvia fruticosa shoot, Crataegus azarolus stem, Crataegus azarolus leave, Varthemia iphionoides shoot, Artemisia herba-alba shoot, Thymus capitatus shoot, Morus nigra leaves and Arum palaestinum leaves) and low antioxidant plants (DPPH-TEAC < 20 mg g(-1)), (i.e., Matricaria aurea shoot, Artemisia judaica shoot, Teucrium polium shoot, Pinus halepenss pollen grains, Sarcopoterium spinosum root, Crataegus azarolus fruit, Inula viscose shoot and Achillea fragrantissima shoot). The antioxidant activity of these plant's extracts and their potential rule in radical scavenging agreed with their potential use by Jordanian population as a traditional anti-diabetic agents.
  • رابط البحث
  • الكلمات المفتاحية
    antioxidant, DPPH, ABTS, TEAC, Polyphenols, GAE, Jordan
In vitro antioxidant and antiproliferative activities of three Malaysian sea cucumber species
  • ملخص البحث
  • The antioxidant and antiproliferative activities of aqueous and organic extracts from three sea cucumber species, Holothuria scabra, Holothuria leucospilota and Stichopus chloronotus were studied. The result showed that aqueous extract of H. leucospilota contains the highest level of total phenols (9.7 mg GAE/g), while the lowest level was obtained from organic extract of H. scabra (1.53 mg GAE/g). An aqueous extract of S. chloronotus was the most efficient extract in scavenging of DPPH free radical, giving IC50= 2.13 mg/ml. The aqueous extracts (50mg/ml) of H. scabra, H. leucospilota and S. chloronotus exhibited high antioxidant activities (77.46%, 64.03% and 80.58%, respectively) against linoleic acid free radical. Only an aqueous extract of S. chloronotus inhibited growth of C33A (human cervical cancer) and A549 (human non-small lung carcinoma) cancer
  • رابط البحث
  • الكلمات المفتاحية
    Sea cucumber, Antioxidant, Antiproliferation.
Antibacterial activity in vitro of Thymus capitatus from Jordan.
  • ملخص البحث
  • This study was carried out to evaluate the antibacterial activity of aqueous and organic extracts of Thymus capitatus L.(Lamiaceae) leaves and stems. Dried ground powder leaves and stems were extracted with water (aqueous extracts), ethanol, dichloromethane and hexane (Soxhlet extracts). The antibacterial activity of these extracts was evaluated against bacteria using disc diffusion method. The result obtained showed that the leaves had stronger antibacterial activity than the stems extracts. The ethanolic extract had the highest yield products and the high antibacterial activity than all other solvents. The results suggest that essential oil as non-polar organic compounds could be the main active compounds in this plant. Therefore the antibacterial activity of leaves ethanol extracts (LEE) was compared with essential oils leaves extracts (LEO) of T. capitatus. The LEO showed greater …
  • رابط البحث
  • الكلمات المفتاحية
    Thymus capitatus, antibacterial, soxhlet extraction, essential oil.
1. Almustafah, A. and Althunibat, O.Y., (2009). Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes. Pakistan Journal of Boilogical Sciences,11 (3): 351-358.
2. Althunibat O.Y., Ridzwan B.H., Taher M., Daud J.M., Ikeda M.A., and Zali B.I. (2009). In Vitro Antioxidant and Antiproliferative Activities of Three Malaysian Sea Cucumber Species. European Journal of Scientific Research, 37 (3): 376-387.
3. Qaralleh H.N., Abboud M.M., Khleifat K., Tarawneh K.A., and Althunibat O.Y., (2009). Antibacterial activity in vitro of Thymus capitatus from Jordan. Pakistan Journal of Pharmaceutical Sciences, 2 (3): 247-251
Althunibat, O. Y., Almustafah, A., Tarawneh K., Khlefat K., Ridzwan B. H., and Qaralleh H. (2010). Protective role of Punica granatum L. peel extract against oxidative damage in experimental diabetic rats. Process Biochemistry, 45: 581-585.

Qaralleh H.N., Khleifat K.M., Tarawneh K.A, Abboud M.M., Idid S.Z., Susanti D., Althunibat O.Y., Chemical composition and antibacterial activities essential oil of Thymus capitatus from Jordan. 23rd Scientific Meeting of the Malaysian Society of Pharmacology and Physiology (23rd MSPP), 12th – 13th May, 2009. Kuala Lumpur, Malaysia. p92.

Althunibat O.Y., Ridzwan B.H., Taher M., Daud J.M.,  and Ikeda M.A.  Antioxidant and antiproliferative activities of malaysian sea cucumber, Holothuria edulis lesson, extracts. Bandung International Conference on Medicinal Chemistry,6th -8th August, 2009.  Bandung, Indonesia. p186.

 Althunibat O.Y., Ridzwan B.H., Taher M., Daud J.M., and Ikeda M.A. Antioxidant and Antiproliferative Activities of Malaysian Sea Cucumber, Stichopus horrens, Extracts. 3rd International Conference for Young Chemists. 23rd- 25th June, 2010. Penang, Malaysia. p170.

Althunibat O.Y., Ridzwan B.H., Taher M., and Daud J.M. Antioxidant and Antiproliferative Activities of Malaysian Sea Cucumber, Holothuria tubulosa, Extracts. 3rd IIUM-iCAST 2010. 26th -29th, November 2010, Kuantan, Malaysia. p

5. Althunibat O.Y., Ridzwan B.H., Taher M., and Daud J.M. In vitro anticancer and antioxidant activities of malaysian sea cucumbers. International Conference for Postgraduate Education (ICPE4). 27th -29th, November, 2010, Kuala Lumpur, Malaysia. P

6. Althunibat O. Y., Ridzwan Ridzwan B.H., Taher M., and Daud J.M. Malaysian Sea Cucumbers: A Promising Source of Anticancer and Antioxidant Agents. IIUM Research, Invention and Innovation Exhibition (IRIIE 2011).9th -10th, February, 2011, IIUM.

. Workshop on Animal Cell culture, Kulliyyah of Pharmacy, IIUM, 29-30 Apr. 2008.
Workshop on Interpretation Data from Various  Spectroscopic analysis, Kulliyyah of Science, IIUM, 2-3 Nov., 2010.
NMR Short Course, Institute Kajian Ubat Semulajadi (iKUS), Universiti Tecknology Mara, UiTM, Puncak Alam, 17-18 Feb, 2011.
 Fundimantal of NMR workshop, Central Laboratory, University of Malaysia Pahang, UMP, 7-8 Dec., 2011.

Althunibat O. Y., Ridzwan Ridzwan B.H., Taher M., and Daud J.M. Malaysian Sea Cucumbers: A Promising Source of Anticancer and Antioxidant Agents. IIUM Research, Invention and Innovation Exhibition (IRIIE 2011). 9th -10th, February, 2011, IIUM. (IRII 2011 Gold winner)

Althunibat O. Y., Recipient of Nich Area Scholarship, IIUM, 2010/2011

2010-2012: Lecturer, Faculty of Dentistry, IIUM. Malaysia 

2012-2015:  Assistant Professor, Faculty of Pharmacy, Alzaytoonah University of Jordan

2015-….: Assistant Professor, Department of Medical Analysis, Princess Aisha Bint Al-Hussein Faculty of Nursing and Health Sciences, Al- Hussein Bin Talal University

2016 -2017: Head of Department of Medical Analysis, Princess Aisha Bint Al-Hussein Faculty of Nursing and Health Sciences, Al- Hussein Bin Talal University.


Medical Biochemistry and Pathophysiology


المؤهلات العلمية و الشهادات

·         PhD in Biomedical Science, International Islamic University Malaysia, IIUM, Malaysia, 2012.
·         M. Sc. in Biology, Mu'tah University, Jordan, 2006.
·         B. Sc. Veterinary Medicine, Jordan University of Science and Technology, Jordan, 2001.

الساعات المكتبية